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71.
Aqueous Solution‐Processable Small Molecular Metal‐Chelate Complex Electrolyte for Flexible All‐Solid State Energy Storage Devices 下载免费PDF全文
A small molecular metal‐chelate complex, tris(8‐hydroxyquinoline‐5‐sulfonic acid) aluminum (AlQSA3), that has three sulfonic acid groups per molecule leading to an excellent solubility in water is reported as a liquid‐free perfect solid‐state electrolyte for flexible film‐type all‐solid‐state energy storage devices. The AlQSA3 material is synthesized by one‐step reaction of aluminum triisopropoxide and 8‐hydroxyquinoline‐5‐sulfonic acid. The aqueous solutions of AlQSA3 are applied to fabricate flexible film‐type all‐solid state electric double layer capacitors with indium‐tin oxide thin film electrodes. The ion conductivity of the AlQSA3 film reaches 0.116 mS cm?1, while a pronounced hysteresis are obtained in the cyclic voltammetry measurement. The AlQSA3 film capacitors exhibit an output voltage of 1.5 V at 20 μA cm?2, which is considerably stable by the repeated operation. In particular, the peak output voltage is well kept even after 180° bending for 500 times in the case of the flexible AlQSA3 film capacitors. 相似文献
72.
Mechanically Recoverable and Highly Efficient Perovskite Solar Cells: Investigation of Intrinsic Flexibility of Organic–Inorganic Perovskite 下载免费PDF全文
Minwoo Park Hae Jin Kim Inyoung Jeong Jinwoo Lee Hyungsuk Lee Hae Jung Son Dae‐Eun Kim Min Jae Ko 《Liver Transplantation》2015,5(22)
Highly efficient solar cells with sustainable performance under severe mechanical deformations are in great demand for future wearable power supply devices. In this regard, numerous studies have progressed to implement flexible architecture to high‐performance devices such as perovskite solar cells. However, the absence of suitable flexible and stretchable materials has been a great obstacle in the replacement of largely utilized transparent conducting oxides that are limited in flexibility. Here, a shape recoverable polymer, Noland Optical Adhesive 63, is utilized as a substrate of perovskite solar cell to enable complete shape recovery of the device upon sub‐millimeter bending radii. The employment of stretchable electrodes prevents mechanical damage of the perovskite layer. Before and after bending at a radius of 1 mm, power conversion efficiency (PCE) is measured to be 10.75% and 10.4%, respectively. Additionally, the shape recoverable device demonstrates a PCE of 6.07% after crumpling. The mechanical properties of all the layers are characterized by nanoindentation. Finite element analysis reveals that the outstanding flexibility of the perovskite layer enables small plastic strain distribution on the deformed device. These results clearly demonstrated that this device has great potential to be utilized in stretchable power supply applications. 相似文献
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通过对猪细小病毒接毒时间TOI、MOI和收毒时间进行优化,开发了一种基于PK-15细胞静置培养的猪细小病毒生产工艺,最大病毒滴度达到107.5TCID50/ml。通过进一步优化接毒时间,成功建立了基于PK-15细胞反应器微载体悬浮培养的猪细小病毒培养工艺,在5L反应器上最大病毒滴度达到107.2TCID50/ml。首次发现乳酸对葡萄糖得率与病毒滴度的正相关性,当猪细小病毒滴度处于最大值时,乳酸对葡萄糖得率也达到最大值,可作为指针病毒滴度及收毒时间的重要参数。 相似文献
75.
目的:观察MUC1对人结肠癌细胞HCT116增殖、侵袭及化疗敏感性的影响。方法:采用MUC1表达阴性的结肠癌细胞株HCT116,通过慢病毒转染、嘌呤霉素筛选、半定量RT-PCR和Western blot鉴定构建稳定表达MUC1的HCT116细胞株;实验分空病毒组和MUC1病毒组;CCK实验和软琼脂克隆形成实验检测两组细胞的增殖能力,Transwell侵袭实验检测两组细胞的侵袭能力;MTT法和流式细胞仪检测两组细胞对奥沙利铂的敏感性,酶底物法检测Caspase-3活性。结果:获得稳定表达MUC1的HCT116细胞株;两组细胞贴壁生长无差异;与空病毒组相比,MUC1病毒组细胞软克隆形成数增加,穿过小室的细胞数增加(P0.05);MUC1病毒组细胞对奥沙利铂的敏感性降低,MUC1病毒组Caspase-3活性水平低于空病毒组(P0.05)。结论:MUC1与结肠癌的非锚定依赖生长、侵袭和化疗敏感性有关。 相似文献
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78.
Moon Hee Jeong Shang-Jin Kim Hara Kang Kye Won Park Woo Jin Park Seung Yul Yang Dong Kwon Yang 《PloS one》2015,10(8)
Cucurbitacin I is a naturally occurring triterpenoid derived from Cucurbitaceae family plants that exhibits a number of potentially useful pharmacological and biological activities. However, the therapeutic impact of cucurbitacin I on the heart has not heretofore been reported. To evaluate the functional role of cucurbitacin I in an in vitro model of cardiac hypertrophy, phenylephrine (PE)-stimulated cardiomyocytes were treated with a sub-cytotoxic concentration of the compound, and the effects on cell size and mRNA expression levels of ANF and β-MHC were investigated. Consequently, PE-induced cell enlargement and upregulation of ANF and β-MHC were significantly suppressed by pretreatment of the cardiomyocytes with cucurbitacin I. Notably, cucurbitacin I also impaired connective tissue growth factor (CTGF) and MAPK signaling, pro-hypertrophic factors, as well as TGF-β/Smad signaling, the important contributing factors to fibrosis. The protective impact of cucurbitacin I was significantly blunted in CTGF-silenced or TGF-β1-silenced hypertrophic cardiomyocytes, indicating that the compound exerts its beneficial actions through CTGF. Taken together, these findings signify that cucurbitacin I protects the heart against cardiac hypertrophy via inhibition of CTGF/MAPK, and TGF- β/Smad-facilitated events. Accordingly, the present study provides new insights into the defensive capacity of cucurbitacin I against cardiac hypertrophy, and further suggesting cucurbitacin I’s utility as a novel therapeutic agent for the management of heart diseases. 相似文献
79.
Sang Ouk Choi Hyun Sun Jeon Joon Young Hyon Yun-Jung Oh Won Ryang Wee Tae-young Chung Young Joo Shin Jeong Won Kim 《PloS one》2015,10(9)
Background
Wound healing of the endothelium occurs through cell enlargement and migration. However, the peripheral corneal endothelium may act as a cell resource for the recovery of corneal endothelium in endothelial injury.Aim
To investigate the recovery process of corneal endothelial cells (CECs) from corneal endothelial injury.Methods
Three patients with unilateral chemical eye injuries, and 15 rabbit eyes with corneal endothelial chemical injuries were studied. Slit lamp examination, specular microscopy, and ultrasound pachymetry were performed immediately after chemical injury and 1, 3, 6, and 9 months later. The anterior chambers of eyes from New Zealand white rabbits were injected with 0.1 mL of 0.05 N NaOH for 10 min (NaOH group). Corneal edema was evaluated at day 1, 7, and 14. Vital staining was performed using alizarin red and trypan blue.Results
Specular microscopy did not reveal any corneal endothelial cells immediately after injury. Corneal edema subsided from the periphery to the center, CEC density increased, and central corneal thickness decreased over time. In the animal study, corneal edema was greater in the NaOH group compared to the control at both day 1 and day 7. At day 1, no CECs were detected at the center and periphery of the corneas in the NaOH group. Two weeks after injury, small, hexagonal CECs were detected in peripheral cornea, while CECs in mid-periphery were large and non-hexagonal.Conclusions
CECs migrated from the periphery to the center of the cornea after endothelial injury. The peripheral corneal endothelium may act as a cell resource for the recovery of corneal endothelium. 相似文献80.
Ji Hye Huh Song Vogue Ahn Sang Baek Koh Eunhee Choi Jang Young Kim Ki-Chul Sung Eung Ju Kim Jeong Bae Park 《PloS one》2015,10(11)